Minimally invasive approaches to hepatic arterial infusion pump placement in metastatic colorectal cancer

Paul J. Shin, T. Peter Kingham


Colorectal cancer is common, and 60% of patients will develop liver metastases over the course of their disease. Over the last two decades, hepatic arterial infusion pump (HAIP) chemotherapy has emerged as an effective and unique form of regional chemotherapy. Traditionally performed as an open operation, minimally invasive (MIS) approaches have been developed to minimize procedure-related morbidity. This paper reviews the indications for HAIP placement, relevant pre- and post-operative considerations, salient operative details in the MIS approach, and common complications related to HAIP placement and chemotherapy.