Mini-invasive pancreaticogastrostomy
Editorial

Mini-invasive pancreaticogastrostomy

Edoardo Rosso1, Giuseppe Zimmitti1, Antonio Iannelli2,3,4, Mohammed Abu Hilal1

1Department of Surgery, Istituto Fondazione Poliambulanza, Brescia, Italy; 2Université Côte d'Azur, Nice, France; 3Digestive Surgery and Liver Transplantation Unit, Centre Hospitalier Universitaire de Nice, Archet 2 Hospital, 151 Route Saint Antoine de Ginestière, BP 3079, Nice Cedex 3, French; 4Inserm, U1065, Team 8 “Hepatic Complications of Obesity and Alcohol” Nice, French

Correspondence to: Edoardo Rosso, MD. Department of Surgery, Istituto Fondazione Poliambulanza, Brescia, Italy. Email: edoardo_rosso@hotmail.com.

Received: 10 March 2020; Accepted: 08 April 2020; Published: 25 January 2021.

doi: 10.21037/ls-2020-mp-07


Video 1 The different step to perform a laparoscopic double purse-string telescoped pancreaticogastrostomy.

Introduction

Two main pancreaoticoenteric anastomosis are conventionally performed after pancreaticoduodenectomy (PD) (1-12): pancreaticojejunostomy and pancreaticogastrostomy (PG). Several publications, review, randomized trials, and meta-analysis have not yet established which pancreaoticoenteric anastomosis is safer (4-18). Our group has a long dating experience with PG after open PD (1-3,18) therefore it was a “natural instinct” to use the same anastomosis in case of laparoscopic PD.

Hereby, we present our current technique of PG underling all the tricks required to reproduce it safely.


Laparoscopic double purse-string telescoped pancreaticogastrostomy (Video 1)

Once completed the resection phase of the PD, the distal pancreatic stump at the level of the superior and inferior border with a 2/0 Prolene stay sutures (Ethicon) the treed should be dived at around 20 cm and keep tougher with a clip to be used later during the intussusception of the pancreatic remnant. The pancreatic remnant is then separated from the splenic artery and vein for at least 3 to 4 cm respecting two “magic rules” should be respected: (I) to avoid the “Pisa Tower effect”, the body of the pancreas should be freed from splenic vessels equally in view to obtain a symmetric stump, indeed it is easier to mobilized the pancreas from the vein then from the artery and the tendency, at beginning of the learning curve, is to leave the splenic artery side shorter than the splenic vein side. (II) To preserve the dorsal pancreatic-artery, when is present, to avoid ischemic pancreatitis. Once the pancreatic stump is mobilized the posterior wall of the stomach is pulled toward the right like a flag and the serous and muscular layer is divided preserving the mucosa layer. The incision is performed at the level of the base of the pancreatic stump and its length is about the length of the cut margin of the pancreas. The first purse-string suture of 2/0 absorbable Monocryl (Ethicon) is applied in a concentric fashion around the posterior gastric incision and includes the seromuscular layers only. The second purse-string suture of 2/0 absorbable Monocryl (Ethicon) is performed in a similar fashion after having divided the mucosa layer and it include the mucosa only. In this case the treed are positioned inside the stomach. At this stage the anterior wall of the stomach is incised at the level of the posterior wall incision, then the pancreatic remnant is gently pulled into the gastric lumen by progressive traction on the 2 stay sutures, the “trick” at this stage is to pull one corner after the other till the pancreatic remnant protrudes 2 to 3 cm in the stomach lumen and in particularly till it stay inside by itself without slipping outside. The 2 purse-string sutures are tightened in order the seromuscular first and the muscular after. It should be avoided to tight to much the sutures the but is to “seal” the anastomosis without strangulating the pancreas. Finally, the anterior gastrotomy is closed with a resorbable 2/0 barbed suture.


Post-operative care

The postoperative care is tailored according to the Fistula Risk Score (ref) in case of low risk score oral intake is started from the 3rd post-operative day (POD) and gradually increased. In case of intermediate or high risk score the oral intake is postpone till POD 5 at the time of the systematic abdominal CT scan, if the CT does not show any significative peri-anastomotic collection than oral intake is allowed, in case of peri-anastomotic collections than oral intake is started after percutaneous drainage.


Acknowledgments

Funding: None.


Footnote

Provenance and Peer Review: This article was commissioned by the Guest Editor (Edoardo Rosso) for the series “Mini-invasive pancreaticoduodenectomy: are we moving from a “feasible” intervention to be considered the standard?” published in Laparoscopic Surgery. The article did not undergo external peer review.

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/ls-2020-mp-07). The series “Mini-invasive pancreaticoduodenectomy: are we moving from a “feasible” intervention to be considered the standard?” was commissioned by the editorial office without any funding or sponsorship. Dr. Edoardo Rosso served as the unpaid Guest Editor of the series and serves as an unpaid editorial board member of Laparoscopic Surgery from Oct 2019 to Sep 2021. Dr. Mohammed Abu Hilal serves as an unpaid editorial board member of Laparoscopic Surgery from June 2019 to May 2021. The authors have no other conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.


References

  1. Addeo P, Rosso E, Fuchshuber P, et al. Double purse-string telescoped pancreaticogastrostomy: an expedient, safe, and easy technique. J Am Coll Surg 2013;216:e27-33. [Crossref] [PubMed]
  2. Rosso E, Bachellier P, Oussoultzoglou E, et al. Toward zero pancreatic fistula after pancreaticoduodenectomy with pancreaticogastrostomy. Am J Surg 2006;191:726-32. [Crossref] [PubMed]
  3. Rosso E, Zimmitti G, Iannelli A, et al. The 'TRIANGLE Operation' by Laparoscopy: Radical Pancreaticoduodenectomy with Major Vascular Resection for Borderline Resectable Pancreatic Head Cancer. Ann Surg Oncol 2020;27:1613-4. [Crossref] [PubMed]
  4. Andrianello S, Marchegiani G, Malleo G, et al. Pancreaticojejunostomy With Externalized Stent vs Pancreaticogastrostomy WithExternalized Stent for Patients With High-Risk Pancreatic Anastomosis: A Single-Center, Phase 3, Randomized Clinical Trial. JAMA Surg 2020;155:313-21. [Crossref] [PubMed]
  5. Hines OJ, Windsor JA. Does Pancreaticogastrostomy Reduce the Risk of Postoperative Pancreatic Fistula After Pancreatoduodenectomy? JAMA Surg 2020;155:321-2. [Crossref] [PubMed]
  6. Halkic N, Kobayashi K, Kokudo T, et al. Pancreaticogastrostomy after pancreaticoduodenectomy without suturing the pancreas. Surg Today 2020;50:200-4. [Crossref] [PubMed]
  7. Puntambekar SP, Mehta MJ, Manchekar MM, et al. Laparoscopic Intracorporeal Pancreaticogastrostomy in Total Laparoscopic Pancreaticoduodenectomy-A Novel Anastomotic Technique. Indian J Surg Oncol 2019;10:274-9. [Crossref] [PubMed]
  8. Eguia E, O'Halloran EA, Borge MA, et al. Four hundred fifty-three consecutive pancreaticoduodenectomies with pancreaticogastrostomy. Am J Surg 2019;218:355-61. [Crossref] [PubMed]
  9. Wakabayashi T, Felli E, Pessaux P. Robotic Double Purse-String Telescoped Pancreaticogastrostomy: How I Do It. World J Surg 2019;43:604-7. [Crossref] [PubMed]
  10. Kang P, Wang Z, Leng K, et al. Binding pancreaticogastrostomy anastomosis in central pancreatectomy: A single center experience. Medicine (Baltimore) 2017;96:e8354. [Crossref] [PubMed]
  11. Knoop RF, Thimme R, Fischer A. Successful two-sided sponge pull-through treatment of anastomotic leakage following pancreaticoduodenectomy with pancreaticogastrostomy. Endoscopy 2017;49:1010-2. [Crossref] [PubMed]
  12. Kostov D, Kobakov G. Is Sutureless Pancreaticogastrostomy More Effective than Single-Layer Duct-to-Mucosa Pancreaticojejunostomy in Pancreaticoduodenectomy? Eurasian J Med 2017;49:79-86. [Crossref] [PubMed]
  13. Lyu Y, Li T, Cheng Y, et al. Pancreaticojejunostomy Versus Pancreaticogastrostomy After Pancreaticoduodenectomy: An Up-to-date Meta-analysis of RCTs Applying the ISGPS (2016) Criteria. Surg Laparosc Endosc Percutan Tech 2018;28:139-46. [Crossref] [PubMed]
  14. Ratnayake CBB, Wells CI, Kamarajah SK, et al. Critical appraisal of the techniques of pancreatic anastomosis following pancreaticoduodenectomy: A network meta-analysis. Int J Surg 2020;73:72-7. [Crossref] [PubMed]
  15. Matsuda M, Haruta S, Shinohara H, et al. Pancreaticogastrostomy in pure laparoscopic pancreaticoduodenectomy--A novel pancreatic-gastric anastomosis technique. BMC Surg 2015;15:80. [Crossref] [PubMed]
  16. Schwarz L, Fleming J, Katz M, et al. Total Laparoscopic Central Pancreatectomy with Pancreaticogastrostomy for High-Risk Cystic Neoplasm. Ann Surg Oncol 2016;23:1035. [Crossref] [PubMed]
  17. Hong D, Liu Y, Peng S, et al. Binding pancreaticogastrostomy in laparoscopic central pancreatectomy: a novel technique in laparoscopic pancreatic surgery. Surg Endosc 2016;30:715-20. [Crossref] [PubMed]
  18. Addeo P, Marzano E, Nobili C, et al. Robotic central pancreatectomy with stented pancreaticogastrostomy: operative details. Int J Med Robot 2011;7:293-7. [Crossref] [PubMed]
doi: 10.21037/ls-2020-mp-07
Cite this article as: Rosso E, Zimmitti G, Iannelli A, Abu Hilal M. Mini-invasive pancreaticogastrostomy. Laparosc Surg 2021;5:1.